The molecular basis of EPCAM expression loss in Lynch syndrome-associated tumors
The molecular basis of EPCAM expression loss in Lynch syndrome-associated tumors
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New York: Elsevier Inc
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Language
English
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Publisher
New York: Elsevier Inc
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Contents
Germline deletions affecting the Epithelial cell adhesion molecule (EPCAM) gene lead to silencing of MSH2 and cause Lynch syndrome. We have recently reported that lack of EPCAM expression occurs in many, but not all tumors from Lynch syndrome patients with EPCAM germline deletions. The differences in EPCAM expression were not related to the localiz...
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Full title
The molecular basis of EPCAM expression loss in Lynch syndrome-associated tumors
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TN_cdi_proquest_journals_1018023773
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1018023773
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ISSN
0893-3952
E-ISSN
1530-0285
DOI
10.1038/modpathol.2012.30
