Tempol Reduces Podocyte Apoptosis via PARP Signaling Pathway in Experimental Diabetes Mellitus
Tempol Reduces Podocyte Apoptosis via PARP Signaling Pathway in Experimental Diabetes Mellitus
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Publisher
Basel: S. Karger AG
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Language
English
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Publisher
Basel: S. Karger AG
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Contents
Background/Aims: In diabetic hypertensive rats, tempol reduces albuminuria by restoring the redox imbalance. Increased formation of reactive oxygen species leading to activation of poly(ADP-ribose) polymerase (PARP)-1 and podocyte loss by apoptosis contribute to albuminuria in diabetes mellitus (DM). In the present study, we investigated the hypoth...
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Full title
Tempol Reduces Podocyte Apoptosis via PARP Signaling Pathway in Experimental Diabetes Mellitus
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TN_cdi_proquest_journals_1023943992
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1023943992
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ISSN
1660-8151
E-ISSN
2235-3186
DOI
10.1159/000337364
