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A single-center, open-label, one-sequence study of dalcetrapib coadministered with ketoconazole, and...

A single-center, open-label, one-sequence study of dalcetrapib coadministered with ketoconazole, and...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1033156760

A single-center, open-label, one-sequence study of dalcetrapib coadministered with ketoconazole, and an in vitro study of the S -methyl metabolite of dalcetrapib

About this item

Full title

A single-center, open-label, one-sequence study of dalcetrapib coadministered with ketoconazole, and an in vitro study of the S -methyl metabolite of dalcetrapib

Publisher

Bridgewater, NJ: EM Inc USA

Journal title

Clinical therapeutics, 2009-03, Vol.31 (3), p.586-599

Language

English

Formats

Publication information

Publisher

Bridgewater, NJ: EM Inc USA

More information

Scope and Contents

Contents

Abstract Background: Dalcetrapib (RO4607381/JTT-705) is currently under clinical investigation for the prevention of cardiovascular events. It inhibits the activity of cholesteryl ester transfer protein and has been reported to increase levels of high-density lipoprotein cholesterol. Objective: Because dalcetrapib is likely to be coadministered wit...

Alternative Titles

Full title

A single-center, open-label, one-sequence study of dalcetrapib coadministered with ketoconazole, and an in vitro study of the S -methyl metabolite of dalcetrapib

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1033156760

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1033156760

Other Identifiers

ISSN

0149-2918

E-ISSN

1879-114X

DOI

10.1016/j.clinthera.2009.02.011

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