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Scaling metagenome sequence assembly with probabilistic de Bruijn graphs

Scaling metagenome sequence assembly with probabilistic de Bruijn graphs

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1033562001

Scaling metagenome sequence assembly with probabilistic de Bruijn graphs

About this item

Full title

Scaling metagenome sequence assembly with probabilistic de Bruijn graphs

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2012-08, Vol.109 (33), p.13272-13277

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Deep sequencing has enabled the investigation of a wide range of environmental microbial ecosystems, but the high memory requirements for de novo assembly of short-read shotgun sequencing data from these complex populations are an increasingly large practical barrier. Here we introduce a memory-efficient graph representation with which we can analy...

Alternative Titles

Full title

Scaling metagenome sequence assembly with probabilistic de Bruijn graphs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1033562001

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1033562001

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.1121464109