Scaling metagenome sequence assembly with probabilistic de Bruijn graphs
Scaling metagenome sequence assembly with probabilistic de Bruijn graphs
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Deep sequencing has enabled the investigation of a wide range of environmental microbial ecosystems, but the high memory requirements for de novo assembly of short-read shotgun sequencing data from these complex populations are an increasingly large practical barrier. Here we introduce a memory-efficient graph representation with which we can analy...
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Scaling metagenome sequence assembly with probabilistic de Bruijn graphs
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TN_cdi_proquest_journals_1033562001
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1033562001
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ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1121464109