EGFRvIII promotes glioma angiogenesis and growth through the NF-[kappa]B, interleukin-8 pathway
EGFRvIII promotes glioma angiogenesis and growth through the NF-[kappa]B, interleukin-8 pathway
About this item
Full title
Author / Creator
Bonavia, R , Inda, M M , Vandenberg, S , Cheng, S-y , Nagane, M , Hadwiger, P , Tan, P , Sah, D W Y , Cavenee, W K and Furnari, F B
Publisher
New York: Nature Publishing Group
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group
Subjects
More information
Scope and Contents
Contents
Sustaining a high growth rate requires tumors to exploit resources in their microenvironment. One example of this is the extensive angiogenesis that is a typical feature of high-grade gliomas. Here, we show that expression of the constitutively active mutant epidermal growth factor receptor, ΔEGFR (EGFRvIII, EGFR*, de2-7EGFR) is associated with sig...
Alternative Titles
Full title
EGFRvIII promotes glioma angiogenesis and growth through the NF-[kappa]B, interleukin-8 pathway
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_1038146177
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1038146177
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2011.563
