Increased A[beta] Production Leads to Intracellular Accumulation of A[beta] in Flotillin-1-Positive...
Increased A[beta] Production Leads to Intracellular Accumulation of A[beta] in Flotillin-1-Positive Endosomes
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Publisher
Basel: S. Karger AG
Journal title
Language
English
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Publisher
Basel: S. Karger AG
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Contents
Extracellular accumulation of Aβ in β-amyloid plaques is thought to be associated with the neurodegeneration observed in Alzheimer's disease (AD) patients, although a lack of correlation with cognitive decline raised doubts on this hypothesis. In different transgenic mouse models Aβ accumulates inside the cells and mice develop behavioral deficits...
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Full title
Increased A[beta] Production Leads to Intracellular Accumulation of A[beta] in Flotillin-1-Positive Endosomes
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TN_cdi_proquest_journals_1069370063
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1069370063
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ISSN
1660-2854
E-ISSN
1660-2862
DOI
10.1159/000101841
