Further Evidence on Mitochondrial Targeting of [beta]-Amyloid and Specificity of [beta]-Amyloid-Indu...
Further Evidence on Mitochondrial Targeting of [beta]-Amyloid and Specificity of [beta]-Amyloid-Induced Mitotoxicity in Neurons
About this item
Full title
Author / Creator
Publisher
Basel: S. Karger AG
Journal title
Language
English
Formats
Publication information
Publisher
Basel: S. Karger AG
More information
Scope and Contents
Contents
Background/Aims: Impaired mitochondrial function has been described in Alzheimer's disease. We previously reported that, in neuronal cells, β-amyloid 1-42 (Aβ1-42) is targeted to mitochondria. We have also reported that, when incubated with isolated rat brain mitochondria, Aβ1-42 inhibits complex IV, uncouples the mitochondrial respiratory chain, a...
Alternative Titles
Full title
Further Evidence on Mitochondrial Targeting of [beta]-Amyloid and Specificity of [beta]-Amyloid-Induced Mitotoxicity in Neurons
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_1081696843
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1081696843
Other Identifiers
ISSN
1660-2854
E-ISSN
1660-2862
DOI
10.1159/000323264
