Laminin induced local axonal translation of [beta]-actin mRNA is impaired in SMN-deficient motoneuro...
Laminin induced local axonal translation of [beta]-actin mRNA is impaired in SMN-deficient motoneurons
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New York: Springer Nature B.V
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English
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New York: Springer Nature B.V
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Reduced levels of the SMN (survival of motoneuron) protein cause spinal muscular atrophy, the main form of motoneuron disease in children and young adults. In cultured motoneurons, reduced SMN levels lead to disturbed axon growth that correlates with reduced actin mRNA and protein in growth cones, indicating that anterograde transport and local tra...
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Laminin induced local axonal translation of [beta]-actin mRNA is impaired in SMN-deficient motoneurons
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TN_cdi_proquest_journals_1104215391
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1104215391
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ISSN
0948-6143
E-ISSN
1432-119X
DOI
10.1007/s00418-012-0989-1
