Somatic von Hippel-Lindau (VHL) gene analysis and clinical outcome under antiangiogenic treatment in...
Somatic von Hippel-Lindau (VHL) gene analysis and clinical outcome under antiangiogenic treatment in metastatic renal cell carcinoma: preliminary results
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Paris: Springer Nature B.V
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English
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Paris: Springer Nature B.V
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Researchers have recently demonstrated a significant activity in the use of antiangiogenic compounds for the treatment of clear-cell metastatic renal cell carcinoma (RCC). The pVHL protein plays an important role in angiogenesis. Germline or somatic alterations of the VHL gene result in an abnormal accumulation of hypoxia inducible factor (HIF) ind...
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Somatic von Hippel-Lindau (VHL) gene analysis and clinical outcome under antiangiogenic treatment in metastatic renal cell carcinoma: preliminary results
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TN_cdi_proquest_journals_1112235548
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1112235548
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ISSN
1776-2596
E-ISSN
1776-260X
DOI
10.1007/s11523-006-0039-9
