Truncated Peroxisome Proliferator-Activated Receptor-[gamma] Coactivator 1[alpha] Splice Variant Is...
Truncated Peroxisome Proliferator-Activated Receptor-[gamma] Coactivator 1[alpha] Splice Variant Is Severely Altered in Huntington's Disease
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Publisher
Basel: S. Karger AG
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Language
English
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Publisher
Basel: S. Karger AG
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Background: Reduced peroxisome proliferator-activated receptor-[gamma] coactivator 1α (PGC1α) gene expression has been observed in striatal cell lines, transgenic mouse models of Huntington's disease (HD), and brain tissue from HD patients. As this protein is a key transcription regulator of the expression of many mitochondrial proteins, these obse...
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Full title
Truncated Peroxisome Proliferator-Activated Receptor-[gamma] Coactivator 1[alpha] Splice Variant Is Severely Altered in Huntington's Disease
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TN_cdi_proquest_journals_1145192962
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1145192962
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ISSN
1660-2854
E-ISSN
1660-2862
DOI
10.1159/000327910
