Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonar...
Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema
About this item
Full title
Author / Creator
Yoshida, Toshinori , Mett, Igor , Bhunia, Anil K , Bowman, Joel , Perez, Mario , Zhang, Li , Gandjeva, Aneta , Zhen, Lijie , Chukwueke, Ugonma , Mao, Tianzhi , Richter, Amy , Brown, Emile , Ashush, Hagit , Notkin, Natalie , Gelfand, Anna , Thimmulappa, Rajesh K , Rangasamy, Tirumalai , Sussan, Thomas , Cosgrove, Gregory , Mouded, Majd , Shapiro, Steven D , Petrache, Irina , Biswal, Shyam , Feinstein, Elena and Tuder, Rubin M
Publisher
London: Nature Publishing Group
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group
Subjects
More information
Scope and Contents
Contents
Rtp801 (also known as Redd1, and encoded by Ddit4), a stress-related protein triggered by adverse environmental conditions, inhibits mammalian target of rapamycin (mTOR) by stabilizing the TSC1-TSC2 inhibitory complex and enhances oxidative stress-dependent cell death. We postulated that Rtp801 acts as a potential amplifying switch in the developme...
Alternative Titles
Full title
Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema
Authors, Artists and Contributors
Author / Creator
Mett, Igor
Bhunia, Anil K
Bowman, Joel
Perez, Mario
Zhang, Li
Gandjeva, Aneta
Zhen, Lijie
Chukwueke, Ugonma
Mao, Tianzhi
Richter, Amy
Brown, Emile
Ashush, Hagit
Notkin, Natalie
Gelfand, Anna
Thimmulappa, Rajesh K
Rangasamy, Tirumalai
Sussan, Thomas
Cosgrove, Gregory
Mouded, Majd
Shapiro, Steven D
Petrache, Irina
Biswal, Shyam
Feinstein, Elena
Tuder, Rubin M
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_1153270982
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1153270982
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
