In vivo genome editing using a high-efficiency TALEN system
In vivo genome editing using a high-efficiency TALEN system
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Author / Creator
Bedell, Victoria M. , Wang, Ying , Campbell, Jarryd M. , Poshusta, Tanya L. , Starker, Colby G. , Krug II, Randall G. , Tan, Wenfang , Penheiter, Sumedha G. , Ma, Alvin C. , Leung, Anskar Y. H. , Fahrenkrug, Scott C. , Carlson, Daniel F. , Voytas, Daniel F. , Clark, Karl J. , Essner, Jeffrey J. and Ekker, Stephen C.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Although zebrafish is an important animal model for basic vertebrate biology and human disease modelling, rapid targeted genome modification has not been possible in this species; here a technique based on improved artificial transcription activator-like effector nucleases (TALENs) allows precise sequence modifications at pre-determined genomic loc...
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Full title
In vivo genome editing using a high-efficiency TALEN system
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TN_cdi_proquest_journals_1210898560
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1210898560
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature11537
