The limitations of renal epithelial cell line HK-2 as a model of drug transporter expression and fun...
The limitations of renal epithelial cell line HK-2 as a model of drug transporter expression and function in the proximal tubule
About this item
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Author / Creator
Publisher
Berlin/Heidelberg: Springer-Verlag
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer-Verlag
Subjects
More information
Scope and Contents
Contents
Acquiring a mechanistic understanding of the processes underlying the renal clearance of drug molecules in man has been hampered by a lack of robust in vitro models of human proximal tubules. Several human renal epithelial cell lines derived from the renal cortex are available, but few have been characterised in detail in terms of transporter expre...
Alternative Titles
Full title
The limitations of renal epithelial cell line HK-2 as a model of drug transporter expression and function in the proximal tubule
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Record Identifier
TN_cdi_proquest_journals_1266441290
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1266441290
Other Identifiers
ISSN
0031-6768
E-ISSN
1432-2013
DOI
10.1007/s00424-012-1163-2
