Molecularly targeted gold nanoparticles enhance the radiation response of breast cancer cells and tu...
Molecularly targeted gold nanoparticles enhance the radiation response of breast cancer cells and tumor xenografts to X-radiation
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Publisher
Boston: Springer US
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Language
English
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Boston: Springer US
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The purpose of this study was to evaluate the effect of molecularly targeted gold nanoparticles (AuNPs) on tumor radiosensitization both in vitro and in vivo. Human Epidermal Growth Factor Receptor-2 (HER-2)-targeted AuNPs (Au–T) were synthesized by conjugating trastuzumab (Herceptin) to 30 nm AuNPs. In vitro, the cytotoxicity of Au-T or non-target...
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Full title
Molecularly targeted gold nanoparticles enhance the radiation response of breast cancer cells and tumor xenografts to X-radiation
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TN_cdi_proquest_journals_1270331007
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1270331007
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ISSN
0167-6806
E-ISSN
1573-7217
DOI
10.1007/s10549-012-2338-4
