NF-[kappa]B is activated in response to temozolomide in an AKT-dependent manner and confers protecti...
NF-[kappa]B is activated in response to temozolomide in an AKT-dependent manner and confers protection against the growth suppressive effect of the drug
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London: BioMed Central
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English
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London: BioMed Central
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Doc number: 252 Abstract Background: Most DNA-damaging chemotherapeutic agents activate the transcription factor nuclear factor κB (NF-κB). However, NF-κB activation can either protect from or contribute to the growth suppressive effects of the agent. We previously showed that the DNA-methylating drug temozolomide (TMZ) activates AKT, a positive mo...
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NF-[kappa]B is activated in response to temozolomide in an AKT-dependent manner and confers protection against the growth suppressive effect of the drug
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TN_cdi_proquest_journals_1271959254
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1271959254
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1479-5876
DOI
10.1186/1479-5876-10-252
