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Ceramide PC102 inhibits melanin synthesis via proteasomal degradation of microphthalmia-associated t...

Ceramide PC102 inhibits melanin synthesis via proteasomal degradation of microphthalmia-associated t...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1272279592

Ceramide PC102 inhibits melanin synthesis via proteasomal degradation of microphthalmia-associated transcription factor and tyrosinase

About this item

Full title

Ceramide PC102 inhibits melanin synthesis via proteasomal degradation of microphthalmia-associated transcription factor and tyrosinase

Publisher

Boston: Springer US

Journal title

Molecular and cellular biochemistry, 2013-03, Vol.375 (1-2), p.81-87

Language

English

Formats

Publication information

Publisher

Boston: Springer US

More information

Scope and Contents

Contents

A few types of ceramide are reported to decrease melanin synthesis. In the present study, we examined the effects of an artificial ceramide analog, PC102, on melanogenesis using a spontaneously immortalized melanocyte cell line (Mel-Ab). PC102 is currently used as a moisturizing additive in a variety of cosmetics. Our data showed that PC102 inhibit...

Alternative Titles

Full title

Ceramide PC102 inhibits melanin synthesis via proteasomal degradation of microphthalmia-associated transcription factor and tyrosinase

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1272279592

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1272279592

Other Identifiers

ISSN

0300-8177

E-ISSN

1573-4919

DOI

10.1007/s11010-012-1530-5

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