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Pharmacokinetic interaction studies of co-administration of ticagrelor and atorvastatin or simvastat...

Pharmacokinetic interaction studies of co-administration of ticagrelor and atorvastatin or simvastat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1287354772

Pharmacokinetic interaction studies of co-administration of ticagrelor and atorvastatin or simvastatin in healthy volunteers

About this item

Full title

Pharmacokinetic interaction studies of co-administration of ticagrelor and atorvastatin or simvastatin in healthy volunteers

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

European journal of clinical pharmacology, 2013-03, Vol.69 (3), p.477-487

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Purpose
Interactions between ticagrelor and atorvastatin or simvastatin were investigated in two-way crossover studies.
Methods
Both studies were open-label for statin; the atorvastatin study was placebo-controlled for ticagrelor. For atorvastatin, volunteers (
n
 = 24) received ticagrelor (loading dose 270 mg; 90 mg twice daily, 7 d...

Alternative Titles

Full title

Pharmacokinetic interaction studies of co-administration of ticagrelor and atorvastatin or simvastatin in healthy volunteers

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1287354772

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1287354772

Other Identifiers

ISSN

0031-6970

E-ISSN

1432-1041

DOI

10.1007/s00228-012-1369-4

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