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Helicobacter pylori Counteracts the Apoptotic Action of Its VacA Toxin by Injecting the CagA Protein...

Helicobacter pylori Counteracts the Apoptotic Action of Its VacA Toxin by Injecting the CagA Protein...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1289054102

Helicobacter pylori Counteracts the Apoptotic Action of Its VacA Toxin by Injecting the CagA Protein into Gastric Epithelial Cells: e1000603

About this item

Full title

Helicobacter pylori Counteracts the Apoptotic Action of Its VacA Toxin by Injecting the CagA Protein into Gastric Epithelial Cells: e1000603

Publisher

San Francisco: Public Library of Science

Journal title

PLoS pathogens, 2009-10, Vol.5 (10)

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

Infection with Helicobacter pylori is responsible for gastritis and gastroduodenal ulcers but is also a high risk factor for the development of gastric adenocarcinoma and lymphoma. The most pathogenic H. pylori strains (i.e., the so-called type I strains) associate the CagA virulence protein with an active VacA cytotoxin but the rationale for this...

Alternative Titles

Full title

Helicobacter pylori Counteracts the Apoptotic Action of Its VacA Toxin by Injecting the CagA Protein into Gastric Epithelial Cells: e1000603

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1289054102

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1289054102

Other Identifiers

ISSN

1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1000603

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