Distinct Roles of Hand2 in Initiating Polarity and Posterior Shh Expression during the Onset of Mous...
Distinct Roles of Hand2 in Initiating Polarity and Posterior Shh Expression during the Onset of Mouse Limb Bud Development: e1000901
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San Francisco: Public Library of Science
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Language
English
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San Francisco: Public Library of Science
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Contents
The polarization of nascent embryonic fields and the endowment of cells with organizer properties are key to initiation of vertebrate organogenesis. One such event is antero-posterior (AP) polarization of early limb buds and activation of morphogenetic Sonic Hedgehog (SHH) signaling in the posterior mesenchyme, which in turn promotes outgrowth and...
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Full title
Distinct Roles of Hand2 in Initiating Polarity and Posterior Shh Expression during the Onset of Mouse Limb Bud Development: e1000901
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TN_cdi_proquest_journals_1313507134
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1313507134
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ISSN
1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1000901
