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Chk2 and p53 Are Haploinsufficient with Dependent and Independent Functions to Eliminate Cells after...

Chk2 and p53 Are Haploinsufficient with Dependent and Independent Functions to Eliminate Cells after...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1313517660

Chk2 and p53 Are Haploinsufficient with Dependent and Independent Functions to Eliminate Cells after Telomere Loss: e1002103

About this item

Full title

Chk2 and p53 Are Haploinsufficient with Dependent and Independent Functions to Eliminate Cells after Telomere Loss: e1002103

Publisher

San Francisco: Public Library of Science

Journal title

PLoS genetics, 2011-06, Vol.7 (6)

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

The mechanisms that cells use to monitor telomere integrity, and the array of responses that may be induced, are not fully defined. To date there have been no studies in animals describing the ability of cells to survive and contribute to adult organs following telomere loss. We developed assays to monitor the ability of somatic cells to proliferat...

Alternative Titles

Full title

Chk2 and p53 Are Haploinsufficient with Dependent and Independent Functions to Eliminate Cells after Telomere Loss: e1002103

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1313517660

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1313517660

Other Identifiers

ISSN

1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1002103

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