Chk2 and p53 Are Haploinsufficient with Dependent and Independent Functions to Eliminate Cells after...
Chk2 and p53 Are Haploinsufficient with Dependent and Independent Functions to Eliminate Cells after Telomere Loss: e1002103
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San Francisco: Public Library of Science
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English
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San Francisco: Public Library of Science
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The mechanisms that cells use to monitor telomere integrity, and the array of responses that may be induced, are not fully defined. To date there have been no studies in animals describing the ability of cells to survive and contribute to adult organs following telomere loss. We developed assays to monitor the ability of somatic cells to proliferat...
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Chk2 and p53 Are Haploinsufficient with Dependent and Independent Functions to Eliminate Cells after Telomere Loss: e1002103
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TN_cdi_proquest_journals_1313517660
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1313517660
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ISSN
1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1002103