Telomere Disruption Results in Non-Random Formation of De Novo Dicentric Chromosomes Involving Acroc...
Telomere Disruption Results in Non-Random Formation of De Novo Dicentric Chromosomes Involving Acrocentric Human Chromosomes: e1001061
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San Francisco: Public Library of Science
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Language
English
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San Francisco: Public Library of Science
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Contents
Genome rearrangement often produces chromosomes with two centromeres (dicentrics) that are inherently unstable because of bridge formation and breakage during cell division. However, mammalian dicentrics, and particularly those in humans, can be quite stable, usually because one centromere is functionally silenced. Molecular mechanisms of centromer...
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Telomere Disruption Results in Non-Random Formation of De Novo Dicentric Chromosomes Involving Acrocentric Human Chromosomes: e1001061
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TN_cdi_proquest_journals_1313524757
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1313524757
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ISSN
1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1001061
