Common Genetic Variation and the Control of HIV-1 in Humans: e1000791
Common Genetic Variation and the Control of HIV-1 in Humans: e1000791
About this item
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Author / Creator
Fellay, Jacques , Ge, Dongliang , Shianna, Kevin V , Colombo, Sara , Ledergerber, Bruno , Cirulli, Elizabeth T , Urban, Thomas J , Zhang, Kunlin , Gumbs, Curtis E , Smith, Jason P , Castagna, Antonella , Cozzi-Lepri, Alessandro , Luca, Andrea De , Easterbrook, Philippa , Günthard, Huldrych F , Mallal, Simon , Mussini, Cristina , Dalmau, Judith , Martinez-Picado, Javier , Miro, José M , Obel, Niels , Wolinsky, Steven M , Martinson, Jeremy J , Detels, Roger , Margolick, Joseph B , Jacobson, Lisa P , Descombes, Patrick , Antonarakis, Stylianos E , Beckmann, Jacques S , Letvin, Norman L , McMichael, Andrew J , Haynes, Barton F , Carrington, Mary , Feng, Sheng , Telenti, Amalio and Goldstein, David B
Publisher
San Francisco: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
San Francisco: Public Library of Science
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More information
Scope and Contents
Contents
To extend the understanding of host genetic determinants of HIV-1 control, we performed a genome-wide association study in a cohort of 2,554 infected Caucasian subjects. The study was powered to detect common genetic variants explaining down to 1.3% of the variability in viral load at set point. We provide overwhelming confirmation of three associa...
Alternative Titles
Full title
Common Genetic Variation and the Control of HIV-1 in Humans: e1000791
Authors, Artists and Contributors
Author / Creator
Ge, Dongliang
Shianna, Kevin V
Colombo, Sara
Ledergerber, Bruno
Cirulli, Elizabeth T
Urban, Thomas J
Zhang, Kunlin
Gumbs, Curtis E
Smith, Jason P
Castagna, Antonella
Cozzi-Lepri, Alessandro
Luca, Andrea De
Easterbrook, Philippa
Günthard, Huldrych F
Mallal, Simon
Mussini, Cristina
Dalmau, Judith
Martinez-Picado, Javier
Miro, José M
Obel, Niels
Wolinsky, Steven M
Martinson, Jeremy J
Detels, Roger
Margolick, Joseph B
Jacobson, Lisa P
Descombes, Patrick
Antonarakis, Stylianos E
Beckmann, Jacques S
Letvin, Norman L
McMichael, Andrew J
Haynes, Barton F
Carrington, Mary
Feng, Sheng
Telenti, Amalio
Goldstein, David B
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_1313535235
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1313535235
Other Identifiers
ISSN
1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1000791
