Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of im...
Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo-controlled, phase 3 trial
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Author / Creator
Demetri, George D, Prof , Reichardt, Peter, Prof , Kang, Yoon-Koo, Prof , Blay, Jean-Yves, Prof , Rutkowski, Piotr, MD , Gelderblom, Hans, MD , Hohenberger, Peter, Prof , Leahy, Michael, FRCP , von Mehren, Margaret, Prof , Joensuu, Heikki, Prof , Badalamenti, Giuseppe, MD , Blackstein, Martin, FRCP , Le Cesne, Axel, MD , Schöffski, Patrick, Prof , Maki, Robert G, Prof , Bauer, Sebastian, MD , Nguyen, Binh Bui, MD , Xu, Jianming, MD , Nishida, Toshirou, MD , Chung, John, MD , Kappeler, Christian, PhD , Kuss, Iris, MD , Laurent, Dirk, MD , Casali, Paolo G, MD , on behalf of all GRID study investigators and GRID study investigators
Publisher
Kidlington: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
Kidlington: Elsevier Ltd
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Scope and Contents
Contents
Summary Background Until now, only imatinib and sunitinib have proven clinical benefit in patients with gastrointestinal stromal tumours (GIST), but almost all metastatic GIST eventually develop resistance to these agents, resulting in fatal disease progression. We aimed to assess efficacy and safety of regorafenib in patients with metastatic or un...
Alternative Titles
Full title
Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo-controlled, phase 3 trial
Authors, Artists and Contributors
Author / Creator
Reichardt, Peter, Prof
Kang, Yoon-Koo, Prof
Blay, Jean-Yves, Prof
Rutkowski, Piotr, MD
Gelderblom, Hans, MD
Hohenberger, Peter, Prof
Leahy, Michael, FRCP
von Mehren, Margaret, Prof
Joensuu, Heikki, Prof
Badalamenti, Giuseppe, MD
Blackstein, Martin, FRCP
Le Cesne, Axel, MD
Schöffski, Patrick, Prof
Maki, Robert G, Prof
Bauer, Sebastian, MD
Nguyen, Binh Bui, MD
Xu, Jianming, MD
Nishida, Toshirou, MD
Chung, John, MD
Kappeler, Christian, PhD
Kuss, Iris, MD
Laurent, Dirk, MD
Casali, Paolo G, MD
on behalf of all GRID study investigators
GRID study investigators
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_1315200039
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1315200039
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(12)61857-1
