High-throughput microplate assay for the determination of drug partition coefficients
High-throughput microplate assay for the determination of drug partition coefficients
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Partition coefficients (
K
p
) of drugs between the phospholipid bilayer and the aqueous phase provide useful information in quantitative structure-activity relationship studies. Hexadecylphosphocholine (HePC) micelles, composed of a zwitterionic hydrophilic surface and a hydrophobic core, mimic the biomembranes and have several advantages...
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Full title
High-throughput microplate assay for the determination of drug partition coefficients
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TN_cdi_proquest_journals_1326290077
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1326290077
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ISSN
1754-2189
E-ISSN
1750-2799
DOI
10.1038/nprot.2010.137
