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Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skele...

Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skele...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1357140912

Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism

About this item

Full title

Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

Diabetologia, 2013-06, Vol.56 (6), p.1372-1382

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

Aims/hypothesis
Although the substitution of saturated fatty acids with oleate has been recommended in the management of type 2 diabetes mellitus, the mechanisms by which oleate improves insulin resistance in skeletal muscle cells are not completely known. Here, we examined whether oleate, through activation of AMP-activated protein kinase (AMPK...

Alternative Titles

Full title

Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1357140912

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1357140912

Other Identifiers

ISSN

0012-186X

E-ISSN

1432-0428

DOI

10.1007/s00125-013-2867-3

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