Paradoxical oncogenesis—the long-term effects of BRAF inhibition in melanoma
Paradoxical oncogenesis—the long-term effects of BRAF inhibition in melanoma
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Although patients with melanoma generally benefit from BRAF or MEK targeted therapies, adverse events can occur on treatment, including the emergence of second malignancies. Evidence suggests unintended or paradoxical activation of MAPK signalling might underlie the majority of these second malignancies. The authors discuss the basis for this parad...
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Full title
Paradoxical oncogenesis—the long-term effects of BRAF inhibition in melanoma
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TN_cdi_proquest_journals_1371849578
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1371849578
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ISSN
1759-4774
E-ISSN
1759-4782
DOI
10.1038/nrclinonc.2013.83
