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Chimeric 5/35 adenovirus-mediated Dickkopf-1 overexpression suppressed tumorigenicity of CD44^sup +^...

Chimeric 5/35 adenovirus-mediated Dickkopf-1 overexpression suppressed tumorigenicity of CD44^sup +^...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1400587741

Chimeric 5/35 adenovirus-mediated Dickkopf-1 overexpression suppressed tumorigenicity of CD44^sup +^ gastric cancer cells via attenuating Wnt signaling

About this item

Full title

Chimeric 5/35 adenovirus-mediated Dickkopf-1 overexpression suppressed tumorigenicity of CD44^sup +^ gastric cancer cells via attenuating Wnt signaling

Publisher

Tokyo: Springer Nature B.V

Journal title

Journal of gastroenterology, 2013-07, Vol.48 (7), p.798

Language

English

Formats

Publication information

Publisher

Tokyo: Springer Nature B.V

More information

Scope and Contents

Contents

Gastric cancer stem cells (CSCs), which require activation of Wnt signaling to maintain their self-renewal and tumorigenicity, are proposed to be critical targets for effective therapy of gastric carcinomas. Gene therapies that are delivered by adenovirus of serotype 5 (Ad5) or chimeric 5/35(Ad5/35) adenovirus have shown promise for treating variou...

Alternative Titles

Full title

Chimeric 5/35 adenovirus-mediated Dickkopf-1 overexpression suppressed tumorigenicity of CD44^sup +^ gastric cancer cells via attenuating Wnt signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1400587741

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1400587741

Other Identifiers

ISSN

0944-1174

E-ISSN

1435-5922

DOI

10.1007/s00535-012-0711-z

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