The citrus flavanone naringenin suppresses CYP1B1 transactivation through antagonising xenobiotic-re...
The citrus flavanone naringenin suppresses CYP1B1 transactivation through antagonising xenobiotic-responsive element binding
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Cambridge, UK: Cambridge University Press
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Language
English
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Publisher
Cambridge, UK: Cambridge University Press
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Contents
Exposure to environmental toxicants or exogenous oestrogen increases the risk of cancer. Some toxicants such as polycyclic aromatic hydrocarbons (PAH) undergo biotransformation to become genotoxic agents. Cytochrome p450 (CYP) 1B1 is an enzyme catalysing this transformation. Consumption of fruit and vegetables is considered to be protective against...
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Full title
The citrus flavanone naringenin suppresses CYP1B1 transactivation through antagonising xenobiotic-responsive element binding
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TN_cdi_proquest_journals_1432704447
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1432704447
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ISSN
0007-1145
E-ISSN
1475-2662
DOI
10.1017/S0007114512003595