A pharmacokinetic interaction study of ticagrelor and digoxin in healthy volunteers
A pharmacokinetic interaction study of ticagrelor and digoxin in healthy volunteers
About this item
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Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Scope and Contents
Contents
Purpose
Ticagrelor is a reversibly binding P2Y
12
receptor antagonist for the prevention of atherothrombotic events in patients with acute coronary syndrome. Previous in vitro studies showed that ticagrelor is a substrate and inhibitor of P-glycoprotein (ABCB1). Therefore, we examined the potential interaction between digoxin, a P-glycopro...
Alternative Titles
Full title
A pharmacokinetic interaction study of ticagrelor and digoxin in healthy volunteers
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TN_cdi_proquest_journals_1433077450
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1433077450
Other Identifiers
ISSN
0031-6970
E-ISSN
1432-1041
DOI
10.1007/s00228-013-1543-3
