Log in to save to my catalogue

The Histone Deacetylase Inhibitor Sodium Butyrate Promotes Cell Death and Differentiation and Reduce...

The Histone Deacetylase Inhibitor Sodium Butyrate Promotes Cell Death and Differentiation and Reduce...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1448960394

The Histone Deacetylase Inhibitor Sodium Butyrate Promotes Cell Death and Differentiation and Reduces Neurosphere Formation in Human Medulloblastoma Cells

About this item

Full title

The Histone Deacetylase Inhibitor Sodium Butyrate Promotes Cell Death and Differentiation and Reduces Neurosphere Formation in Human Medulloblastoma Cells

Publisher

Boston: Springer US

Journal title

Molecular neurobiology, 2013-12, Vol.48 (3), p.533-543

Language

English

Formats

Publication information

Publisher

Boston: Springer US

More information

Scope and Contents

Contents

Increasing evidence suggests that alterations in epigenetic mechanisms regulating chromatin state play a role in the pathogenesis of medulloblastoma (MB), the most common malignant brain tumor of childhood. Histone deacetylase (HDAC) inhibitors, which increase chromatin relaxation, have been shown to display anticancer activities. Here we show that...

Alternative Titles

Full title

The Histone Deacetylase Inhibitor Sodium Butyrate Promotes Cell Death and Differentiation and Reduces Neurosphere Formation in Human Medulloblastoma Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1448960394

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1448960394

Other Identifiers

ISSN

0893-7648

E-ISSN

1559-1182

DOI

10.1007/s12035-013-8441-7

How to access this item