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Selecting antagonistic antibodies that control differentiation through inducible expression in embry...

Selecting antagonistic antibodies that control differentiation through inducible expression in embry...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1449199506

Selecting antagonistic antibodies that control differentiation through inducible expression in embryonic stem cells

About this item

Full title

Selecting antagonistic antibodies that control differentiation through inducible expression in embryonic stem cells

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (44), p.17802-17807

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Antibodies that modulate receptor function have great untapped potential in the control of stem cell differentiation. In contrast to many natural ligands, antibodies are stable, exquisitely specific, and are unaffected by the regulatory mechanisms that act on natural ligands. Here we describe an innovative system for identifying such antibodies by...

Alternative Titles

Full title

Selecting antagonistic antibodies that control differentiation through inducible expression in embryonic stem cells

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1449199506

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1449199506

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1312062110

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