Selecting antagonistic antibodies that control differentiation through inducible expression in embry...
Selecting antagonistic antibodies that control differentiation through inducible expression in embryonic stem cells
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Antibodies that modulate receptor function have great untapped potential in the control of stem cell differentiation. In contrast to many natural ligands, antibodies are stable, exquisitely specific, and are unaffected by the regulatory mechanisms that act on natural ligands. Here we describe an innovative system for identifying such antibodies by...
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Full title
Selecting antagonistic antibodies that control differentiation through inducible expression in embryonic stem cells
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TN_cdi_proquest_journals_1449199506
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1449199506
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1312062110