Deciphering the Structural Basis of Eukaryotic Protein Kinase Regulation: e1001680
Deciphering the Structural Basis of Eukaryotic Protein Kinase Regulation: e1001680
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San Francisco: Public Library of Science
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Language
English
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Publisher
San Francisco: Public Library of Science
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Contents
Eukaryotic protein kinases (EPKs) regulate numerous signaling processes by phosphorylating targeted substrates through the highly conserved catalytic domain. Our previous computational studies proposed a model stating that a properly assembled nonlinear motif termed the Regulatory (R) spine is essential for catalytic activity of EPKs. Here we defin...
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Full title
Deciphering the Structural Basis of Eukaryotic Protein Kinase Regulation: e1001680
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TN_cdi_proquest_journals_1458892255
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1458892255
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ISSN
1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.1001680
