Combining two strategies to improve perfusion and drug delivery in solid tumors
Combining two strategies to improve perfusion and drug delivery in solid tumors
About this item
Full title
Author / Creator
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Blood perfusion in tumors can be significantly lower than that in the surrounding normal tissue owing to the leakiness and/or compression of tumor blood vessels. Impaired perfusion reduces oxygen supply and results in a hypoxic microenvironment. Hypoxia promotes tumor progression and immunosuppression, and enhances the invasive and metastatic poten...
Alternative Titles
Full title
Combining two strategies to improve perfusion and drug delivery in solid tumors
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_proquest_journals_1460249576
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1460249576
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1318415110
