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Next-Generation Integrase Inhibitors: Where to After Raltegravir?

Next-Generation Integrase Inhibitors: Where to After Raltegravir?

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1466148633

Next-Generation Integrase Inhibitors: Where to After Raltegravir?

About this item

Full title

Next-Generation Integrase Inhibitors: Where to After Raltegravir?

Publisher

Cham: Springer International Publishing AG

Journal title

Drugs (New York, N.Y.), 2013-03, Vol.73 (3), p.213-228

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing AG

More information

Scope and Contents

Contents

The integrase enzyme facilitates the incorporation of HIV-1 proviral DNA into the host cell genome and catalyses a function vital to viral replication. Inhibitors of this enzyme represent the newest class of antiretroviral drugs in our armamentarium to treat HIV-1 infection. Raltegravir, an integrase strand transfer inhibitor, was the first drug of...

Alternative Titles

Full title

Next-Generation Integrase Inhibitors: Where to After Raltegravir?

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1466148633

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1466148633

Other Identifiers

ISSN

0012-6667

E-ISSN

1179-1950

DOI

10.1007/s40265-013-0015-5

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