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Dimerization of LT[Beta]R by LT[Alpha]^sub 1^[Beta]^sub 2^ is necessary and sufficient for signal tr...

Dimerization of LT[Beta]R by LT[Alpha]^sub 1^[Beta]^sub 2^ is necessary and sufficient for signal tr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1468661176

Dimerization of LT[Beta]R by LT[Alpha]^sub 1^[Beta]^sub 2^ is necessary and sufficient for signal transduction

About this item

Full title

Dimerization of LT[Beta]R by LT[Alpha]^sub 1^[Beta]^sub 2^ is necessary and sufficient for signal transduction

Publisher

Washington: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (49), p.19896

Language

English

Formats

Publication information

Publisher

Washington: National Academy of Sciences

More information

Scope and Contents

Contents

Homotrimeric TNF superfamily ligands signal by inducing trimers of their cognate receptors. As a biologically active heterotrimer, Lymphotoxin(LT)α...β... is unique in the TNF superfamily. How the three unique potential receptor-binding interfaces in LTα...β... trigger signaling via LTβ Receptor (LTβR) resulting in lymphoid organogenesis and propag...

Alternative Titles

Full title

Dimerization of LT[Beta]R by LT[Alpha]^sub 1^[Beta]^sub 2^ is necessary and sufficient for signal transduction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1468661176

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1468661176

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

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