Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adeno...
Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial
About this item
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Author / Creator
Fuchs, Charles S, Dr Prof , Tomasek, Jiri, MD , Yong, Cho Jae, Prof , Dumitru, Filip, MD , Passalacqua, Rodolfo, MD , Goswami, Chanchal, Prof , Safran, Howard, Prof , dos Santos, Lucas Vieira, MD , Aprile, Giuseppe, MD , Ferry, David R, Prof , Melichar, Bohuslav, Prof , Tehfe, Mustapha, MD , Topuzov, Eldar, Prof , Zalcberg, John Raymond, Prof , Chau, Ian, MD , Campbell, William, Prof , Sivanandan, Choondal, MD , Pikiel, Joanna, MD , Koshiji, Minori, MD , Hsu, Yanzhi, PhD , Liepa, Astra M, PharmD , Gao, Ling, PhD , Schwartz, Jonathan D, MD , Tabernero, Josep, MD , for the REGARD Trial Investigators and REGARD Trial Investigators
Publisher
Kidlington: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Kidlington: Elsevier Ltd
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More information
Scope and Contents
Contents
Summary Background Vascular endothelial growth factor (VEGF) and VEGF receptor-2 (VEGFR-2)-mediated signalling and angiogenesis can contribute to the pathogenesis and progression of gastric cancer. We aimed to assess whether ramucirumab, a monoclonal antibody VEGFR-2 antagonist, prolonged survival in patients with advanced gastric cancer. Methods W...
Alternative Titles
Full title
Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial
Authors, Artists and Contributors
Author / Creator
Tomasek, Jiri, MD
Yong, Cho Jae, Prof
Dumitru, Filip, MD
Passalacqua, Rodolfo, MD
Goswami, Chanchal, Prof
Safran, Howard, Prof
dos Santos, Lucas Vieira, MD
Aprile, Giuseppe, MD
Ferry, David R, Prof
Melichar, Bohuslav, Prof
Tehfe, Mustapha, MD
Topuzov, Eldar, Prof
Zalcberg, John Raymond, Prof
Chau, Ian, MD
Campbell, William, Prof
Sivanandan, Choondal, MD
Pikiel, Joanna, MD
Koshiji, Minori, MD
Hsu, Yanzhi, PhD
Liepa, Astra M, PharmD
Gao, Ling, PhD
Schwartz, Jonathan D, MD
Tabernero, Josep, MD
for the REGARD Trial Investigators
REGARD Trial Investigators
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_1473891640
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1473891640
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(13)61719-5
