opioid receptor gene variant OPRM1 118 A>G: a summary of its molecular and clinical consequences for...
opioid receptor gene variant OPRM1 118 A>G: a summary of its molecular and clinical consequences for pain
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Publisher
London: Future Medicine Ltd
Journal title
Language
English
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Publisher
London: Future Medicine Ltd
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Contents
The human µ-opioid receptor variant 118 A>G (rs1799971) has become one of the most analyzed genetic variants in the pain field. At the molecular level, the variant reduces opioid receptor signaling efficiency and expression, the latter probably via a genetic-epigenetic interaction. In experimental settings, the variant was reproducibly associated w...
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opioid receptor gene variant OPRM1 118 A>G: a summary of its molecular and clinical consequences for pain
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TN_cdi_proquest_journals_1477547984
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1477547984
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ISSN
1462-2416
E-ISSN
1744-8042
DOI
10.2217/pgs.13.187
