TGF-[Beta] directs trafficking of the epithelial sodium channel ENaC which has implications for ion...
TGF-[Beta] directs trafficking of the epithelial sodium channel ENaC which has implications for ion and fluid transport in acute lung injury
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Author / Creator
Peters, Dorothea M , Vadász, István , Wujak, Lukasz , Wygrecka, Malgorzata , Olschewski, Andrea , Becker, Christin , Herold, Susanne , Papp, Rita , Mayer, Konstantin , Rummel, Sebastian , Brandes, Ralph P , Günther, Andreas , Waldegger, Siegfried , Eickelberg, Oliver , Seeger, Werner and Morty, Rory E
Publisher
Washington: National Academy of Sciences
Journal title
Language
English
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Publisher
Washington: National Academy of Sciences
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Scope and Contents
Contents
TGF-β is a pathogenic factor in patients with acute respiratory distress syndrome (ARDS), a condition characterized by alveolar edema. A unique TGF-β pathway is described, which rapidly promoted internalization of the αβγ epithelial sodium channel (ENaC) complex from the alveolar epithelial cell surface, leading to persistence of pulmonary edema. T...
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Full title
TGF-[Beta] directs trafficking of the epithelial sodium channel ENaC which has implications for ion and fluid transport in acute lung injury
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TN_cdi_proquest_journals_1492272459
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1492272459
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
