Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiot...
Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Recent developments in next-generation sequencing technologies have brought recognition of microbial genomes as a rich resource for novel natural product discovery. However, owing to the scarcity of efficient procedures to connect genes to molecules, only a small fraction of secondary metabolomes have been investigated to date. Transformation-assoc...
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Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A
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TN_cdi_proquest_journals_1497039655
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1497039655
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1319584111