Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrel
Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrel
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United States: Mosby, Inc
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English
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United States: Mosby, Inc
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Background Clopidogrel is activated by CYP2C19, which also metabolizes proton pump inhibitors (PPI). As proton pump inhibitors are metabolized to varying degrees by CYP2C19, we hypothesized that the reported negative omeprazole-clopidogrel drug interaction may not be a class effect. Methods Responsiveness to clopidogrel was assessed by the vasodila...
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Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrel
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TN_cdi_proquest_journals_1504614682
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1504614682
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ISSN
0002-8703
E-ISSN
1097-6744
DOI
10.1016/j.ahj.2008.09.017