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Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrel

Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrel

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1504614682

Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrel

About this item

Full title

Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrel

Publisher

United States: Mosby, Inc

Journal title

The American heart journal, 2009, Vol.157 (1), p.148.e1-148.e5

Language

English

Formats

Publication information

Publisher

United States: Mosby, Inc

More information

Scope and Contents

Contents

Background Clopidogrel is activated by CYP2C19, which also metabolizes proton pump inhibitors (PPI). As proton pump inhibitors are metabolized to varying degrees by CYP2C19, we hypothesized that the reported negative omeprazole-clopidogrel drug interaction may not be a class effect. Methods Responsiveness to clopidogrel was assessed by the vasodila...

Alternative Titles

Full title

Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrel

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1504614682

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1504614682

Other Identifiers

ISSN

0002-8703

E-ISSN

1097-6744

DOI

10.1016/j.ahj.2008.09.017

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