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Structural bases for the interaction and stabilization of the human amino acid transporter LAT2 with...

Structural bases for the interaction and stabilization of the human amino acid transporter LAT2 with...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1504816469

Structural bases for the interaction and stabilization of the human amino acid transporter LAT2 with its ancillary protein 4F2hc

About this item

Full title

Structural bases for the interaction and stabilization of the human amino acid transporter LAT2 with its ancillary protein 4F2hc

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (8), p.2966-2971

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Heteromeric amino acid transporters (HATs) are the unique example, known in all kingdoms of life, of solute transporters composed of two subunits linked by a conserved disulfide bridge. In metazoans, the heavy subunit is responsible for the trafficking of the heterodimer to the plasma membrane, and the light subunit is the transporter. HATs are inv...

Alternative Titles

Full title

Structural bases for the interaction and stabilization of the human amino acid transporter LAT2 with its ancillary protein 4F2hc

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1504816469

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1504816469

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.1323779111

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