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[18F]NS10743: Characterisation of a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR)...

[18F]NS10743: Characterisation of a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR)...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1506899526

[18F]NS10743: Characterisation of a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) radioligand in pig brain by PET

About this item

Full title

[18F]NS10743: Characterisation of a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) radioligand in pig brain by PET

Publisher

Amsterdam: Elsevier Limited

Journal title

NeuroImage (Orlando, Fla.), 2010-08, Vol.52 (S1), p.S49

Language

English

Formats

Publication information

Publisher

Amsterdam: Elsevier Limited

Subjects

Subjects and topics

More information

Scope and Contents

Contents

The challenge to improve the binding potential of [18F]NS10743, limited mainly by the low density of [alpha]7 nAChR expression in the brain and reflected by rather small regional differences in baseline uptake of [18F]NS10743, will be met by further modifications of the NS10743 core structure intended to increase the target affinity of the tracer c...

Alternative Titles

Full title

[18F]NS10743: Characterisation of a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) radioligand in pig brain by PET

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1506899526

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1506899526

Other Identifiers

ISSN

1053-8119

E-ISSN

1095-9572

DOI

10.1016/j.neuroimage.2010.04.230

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