Occupancy of dopamine D2/D3 receptors in rat brain by endogenous dopamine measured with the agonist...
Occupancy of dopamine D2/D3 receptors in rat brain by endogenous dopamine measured with the agonist positron emission tomography radioligand [11C]MNPA
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Author / Creator
Seneca, Nicholas , Zoghbi, S.S. , Skinbjerg, M. , Liow, J.S. , Hong, J. , Sibley, D.R. , Pike, V.W. , Halldin, C. and Innis, R.B.
Publisher
Amsterdam: Elsevier Limited
Journal title
Language
English
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Publication information
Publisher
Amsterdam: Elsevier Limited
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Scope and Contents
Contents
Ex vivo measurements of the percentage of parent and radiometabolites in rat brain after radioligand injection during baseline and dopamine depletion conditions were not significantly different. [...]dopamine depletion did not increase the PET measurements via an effect on radiotracer metabolism. Chronic depletion of dopamine, (as in Parkinson's di...
Alternative Titles
Full title
Occupancy of dopamine D2/D3 receptors in rat brain by endogenous dopamine measured with the agonist positron emission tomography radioligand [11C]MNPA
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_journals_1506905093
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1506905093
Other Identifiers
ISSN
1053-8119
E-ISSN
1095-9572
DOI
10.1016/j.neuroimage.2008.04.106
