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Impact of variable CYP genotypes on breast cancer relapse in patients undergoing adjuvant tamoxifen...

Impact of variable CYP genotypes on breast cancer relapse in patients undergoing adjuvant tamoxifen...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1528204967

Impact of variable CYP genotypes on breast cancer relapse in patients undergoing adjuvant tamoxifen therapy

About this item

Full title

Impact of variable CYP genotypes on breast cancer relapse in patients undergoing adjuvant tamoxifen therapy

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Cancer chemotherapy and pharmacology, 2014-06, Vol.73 (6), p.1181-1188

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Background
Tamoxifen is frequently used for the treatment of hormone receptor positive breast cancer (BC). Mainly CYP2D6 is responsible for the transformation to therapeutically active metabolites, but CYP2C19, CYP2C9 and CYP2B6 also are involved. We investigated the impact of polymorphisms within the genes encoding these CYP enzymes on the rela...

Alternative Titles

Full title

Impact of variable CYP genotypes on breast cancer relapse in patients undergoing adjuvant tamoxifen therapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1528204967

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1528204967

Other Identifiers

ISSN

0344-5704

E-ISSN

1432-0843

DOI

10.1007/s00280-014-2453-5

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