Phosphorylation Modulates Clearance of Alpha-Synuclein Inclusions in a Yeast Model of Parkinson's Di...
Phosphorylation Modulates Clearance of Alpha-Synuclein Inclusions in a Yeast Model of Parkinson's Disease: e1004302
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San Francisco: Public Library of Science
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English
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San Francisco: Public Library of Science
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Alpha-synuclein (aSyn) is the main component of proteinaceous inclusions known as Lewy bodies (LBs), the typical pathological hallmark of Parkinson's disease (PD) and other synucleinopathies. Although aSyn is phosphorylated at low levels under physiological conditions, it is estimated that ~90% of aSyn in LBs is phosphorylated at S129 (pS129). Neve...
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Phosphorylation Modulates Clearance of Alpha-Synuclein Inclusions in a Yeast Model of Parkinson's Disease: e1004302
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TN_cdi_proquest_journals_1536052734
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1536052734
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1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1004302
