The metabolite [alpha]-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR
The metabolite [alpha]-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR
About this item
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Author / Creator
Chin, Randall M , Fu, Xudong , Pai, Melody Y , Vergnes, Laurent , Hwang, Heejun , Deng, Gang , Diep, Simon , Lomenick, Brett , Meli, Vijaykumar S , Monsalve, Gabriela C , Hu, Eileen , Whelan, Stephen A , Wang, Jennifer X , Jung, Gwanghyun , Solis, Gregory M , Fazlollahi, Farbod , Kaweeteerawat, Chitrada , Quach, Austin , Nili, Mahta , Krall, Abby S , Godwin, Hilary A , Chang, Helena R , Faull, Kym F , Guo, Feng , Jiang, Meisheng , Trauger, Sunia A , Saghatelian, Alan , Braas, Daniel , Christofk, Heather R , Clarke, Catherine F , Teitell, Michael A , Petrascheck, Michael , Reue, Karen , Jung, Michael E , Frand, Alison R and Huang, Jing
Publisher
London: Nature Publishing Group
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group
Subjects
More information
Scope and Contents
Contents
Metabolism and ageing are intimately linked. Compared with ad libitum feeding, dietary restriction consistently extends lifespan and delays age-related diseases in evolutionarily diverse organisms. Similar conditions of nutrient limitation and genetic or pharmacological perturbations of nutrient or energy metabolism also have longevity benefits. Re...
Alternative Titles
Full title
The metabolite [alpha]-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR
Authors, Artists and Contributors
Author / Creator
Fu, Xudong
Pai, Melody Y
Vergnes, Laurent
Hwang, Heejun
Deng, Gang
Diep, Simon
Lomenick, Brett
Meli, Vijaykumar S
Monsalve, Gabriela C
Hu, Eileen
Whelan, Stephen A
Wang, Jennifer X
Jung, Gwanghyun
Solis, Gregory M
Fazlollahi, Farbod
Kaweeteerawat, Chitrada
Quach, Austin
Nili, Mahta
Krall, Abby S
Godwin, Hilary A
Chang, Helena R
Faull, Kym F
Guo, Feng
Jiang, Meisheng
Trauger, Sunia A
Saghatelian, Alan
Braas, Daniel
Christofk, Heather R
Clarke, Catherine F
Teitell, Michael A
Petrascheck, Michael
Reue, Karen
Jung, Michael E
Frand, Alison R
Huang, Jing
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_1541466206
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1541466206
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
