Impaired Activation of the Nrf2-ARE Signaling Pathway Undermines H2O2-Induced Oxidative Stress Respo...
Impaired Activation of the Nrf2-ARE Signaling Pathway Undermines H2O2-Induced Oxidative Stress Response: A Possible Mechanism for Melanocyte Degeneration in Vitiligo
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Jian, Zhe , Li, Kai , Song, Pu , Zhu, Guannan , Zhu, Longfei , Cui, Tingting , Liu, Bangmin , Tang, Lingzhen , Wang, Xiaowen , Wang, Gang , Gao, Tianwen and Li, Chunying
Publisher
United States: Elsevier Inc
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English
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United States: Elsevier Inc
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Vitiligo melanocytes possess higher susceptibility to oxidative insults. Consistent with this, impairment of the antioxidant defense system has been reported to be involved in the onset and progression of vitiligo. Our previous study showed that the nuclear factor E2-related factor 2–antioxidant response element (Nrf2-ARE) pathway and its downstrea...
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Impaired Activation of the Nrf2-ARE Signaling Pathway Undermines H2O2-Induced Oxidative Stress Response: A Possible Mechanism for Melanocyte Degeneration in Vitiligo
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TN_cdi_proquest_journals_1545517798
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1545517798
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ISSN
0022-202X
E-ISSN
1523-1747
DOI
10.1038/jid.2014.152
