The LTK63 adjuvant improves protection conferred by Ag85B DNA-protein prime-boosting vaccination aga...
The LTK63 adjuvant improves protection conferred by Ag85B DNA-protein prime-boosting vaccination againstMycobacterium tuberculosisinfection by dampening IFN-[gamma] response
About this item
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Publisher
Kidlington: Elsevier Limited
Journal title
Language
English
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Publisher
Kidlington: Elsevier Limited
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Scope and Contents
Contents
T helper type-1 response is essential to controlMycobacterium tuberculosis(MTB) infection but excessive antigen-mediated inflammation concurs to pathology. In mice challenged with MTB, the protection elicited by an Ag85B-encoding DNA vaccine, was lost when mice were boosted with Ag85B-protein in the absence of adjuvant. This effect was due to the e...
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Full title
The LTK63 adjuvant improves protection conferred by Ag85B DNA-protein prime-boosting vaccination againstMycobacterium tuberculosisinfection by dampening IFN-[gamma] response
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Record Identifier
TN_cdi_proquest_journals_1547166017
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1547166017
Other Identifiers
ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2008.05.050
