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D2dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine:...

D2dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine:...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1549930978

D2dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: A PET study in a receptor internalization-deficient mouse model

About this item

Full title

D2dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: A PET study in a receptor internalization-deficient mouse model

Publisher

Amsterdam: Elsevier Limited

Journal title

NeuroImage (Orlando, Fla.), 2010-05, Vol.50 (4), p.1402

Language

English

Formats

Publication information

Publisher

Amsterdam: Elsevier Limited

More information

Scope and Contents

Contents

Dopamine released by amphetamine decreases thein vivobinding of PET radioligands to the dopamine D2receptor. Although concentrations of extracellular dopamine largely return to baseline within 1 to 2 h after amphetamine treatment, radioligand binding remains decreased for several hours. The purpose of this study was to determine whether the prolong...

Alternative Titles

Full title

D2dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: A PET study in a receptor internalization-deficient mouse model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1549930978

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1549930978

Other Identifiers

ISSN

1053-8119

E-ISSN

1095-9572

DOI

10.1016/j.neuroimage.2010.01.055

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