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Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila

Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1549957005

Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila

About this item

Full title

Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (29), p.E2967-E2976

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The type II clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) system has emerged recently as a powerful method to manipulate the genomes of various organisms. Here, we report a toolbox for high-efficiency genome engineering of Drosophila melanogaster consisting of transgenic Cas9 lines and versatile guide RN...

Alternative Titles

Full title

Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1549957005

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1549957005

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1405500111

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